NOT ALL BRAND NAME BIOLOGICS AND BIOSIMILARS WORK IN THE SAME WAY
Did you know…
-
The “mechanism of action” of a
brand name biologic or biosimilar is
what the drug does inside the body
to treat a disease – in other words,
how it works1 -
There are multiple “classes” of brand name biologics and biosimilars for chronic immunological diseases (e.g., plaque psoriasis, Crohn’s disease, ulcerative colitis, and rheumatoid arthritis)2
-
Each class is categorized by what
the biologic treatments target within
the body2
Some of the targets that brand name biologics and/or biosimilars may interact with include:3
-
Tumour necrosis
factor alpha (TNFα) -
B cells
(Anti-CD20) -
T cells
(T cell activation inhibitors/
co-stimulation modulators) -
Interleukins
(IL-6, IL-12/23, IL-17,
and IL-23)
Not all brand-name biologics have a corresponding biosimilar